Chippenham went into this game unbeaten in their last fifteen league games, a streak the Rebels ended with ease.
Slough started the game off very brightly and took the lead within the first two minutes.
Gabe George beat his man with ease on the left wing, before putting in a dangerous ball which bobbled its way to Alexander, who was left unmarked in the box to tuck his effort home to give the hosts the lead.
The Rebels could have doubled their lead in quick fashion. Matt Lench delivered a fantastic ball into the box towards Elliot Benyon, but his headed effort was denied by a brilliant save by Will Henry.
Alexander was denied a second goal as his close range attempt was stopped by Henry, who kept the scoreline respectable in the first half.
Lee Togwell could have scored an absolute rocket from the edge of the box as a low cross from Lench deflected into his path, but his powerful effort was parried away by Henry.
Slough never took their foot off the gas pedal and their persistence paid off as they doubled their lead just after halfway through the first half.
Alexander initially tried to flick the ball towards goal, but he had another chance to shoot and curled in his second goal of the afternoon, to give Slough a 2-0 lead in the 27th minute.
In the second half, Slough increased their intensity, particularly Alexander.
Johnny Goddard was brilliant in the build-up play in the left flank, playing in Alexander who was once again unmarked in the penalty area to secure his second hat-trick at Arbour Park this season – his first being for Welling United against the Rebels earlier in the season.
It also marked the first time since February 2020 that a Slough player hit a treble.
Slough were not done applying pressure on Chippenham. Matt Lench delivered a great ball into the box, and Shane Bush was denied by the crossbar.
Just a minute later, only a stunning save from Henry kept out another bullet header from Bush after Lench swung in another corner.
But Slough – and George Alexander – got their fourth goal just past the hour mark. Will King was sloppy in possession and Alexander was once again lurking and pounced at the opportunity to score his fourth of the afternoon with a powerful finish.
Chippenham got a consolation goal as Ed Williams played a low driven cross towards Alex Bray at the far post to fire it home, but there was little hope for the visitors to turn around such a deficit.
The Rebels made sure those hopes of a remarkable comeback were put to bed as Josh Jackman finished off a brilliant team goal filled with intricate passing around the Chippenham box to grab a fifth goal for the hosts.
And in the 84th minute, Slough added a sixth goal.
Substitute Francis Amartey - making his first appearance in almost seven weeks due to an hamstring injury - saw a deflected effort hit the crossbar. From the resulting corner, Elliot Benyon headed home at the far post after Temi Eweka flicked the ball on.
Good Friday delivered for Slough fans with the Rebels now seven points clear of the relegation zone, with a trip to Taunton coming up on Easter Monday.
Image: George Beck
Chippenham Town Lineup
Will Henry, Aaron Simpson (Caine Bradbury 46), Spencer Hamilton, Ollie Tomlinson, Tom Mehew, Matt McClure (Joe Parker 67), Alex Bray, Owen Windsor, Ed Williams, Luke Russe (Alefe Santos 72), Will King. Unused substitutes: Craig Fasanmade, Joe Hanks.